Abstract Library

#1893 Peripheral Blood Biomarkers of Systemic Inflammation May Be Prognostic in Metastatic Gastroenteropancreatic Neuroendocrine Tumour (GEPNET) Patients Following 177Lu-DOTATATE (LuTate)

Introduction: LuTate is a treatment for well-differentiated NETs with adequate somatostatin receptor expression. Prognostic biomarkers in this population are lacking. Neutrophil-to-lymphocyte ratio (NLR) is prognostic in the majority of solid tumours but is reported to have less value in indolent well-differentiated NETs.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author:

Authors: Hayes A, Hosking E, Thomas D, Sjoquist K, Chan D,

Keywords: prognostic, biomarker, PRRT, LuTate,

#1505 A Blood-Based Multi-Transcript Test, the NETest, Predicts and Defines PRRT Efficacy in Neuroendocrine Tumors

Introduction: Peptide receptor radionuclide therapy (PRRT) is an effective NET treatment. Predicting response is based on somatostatin receptor expression and efficacy evaluated by RECIST criteria. Both have limited accuracy. The NETest measures tumor activity in blood and correlates cell signaling and metabolism directly with tumor activity.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: Bodei L

Authors: Bodei L, Kidd M, Severi S, Drozdov I, Nicolini S,

Keywords: NETest, PRRT,

#1330 Pancreatic Neuroendocrine Neoplasms: Magnetic Resonance Imaging Features and Correlation with Their Histological Grade

Introduction: Pancreatic neuroendocrine neoplasms (PanNENs) have different biological behavior and prognosis according to their histological grade. At present, few data are available regarding the value of imaging techniques in predicting the grade of PanNENs.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author:

Authors: De Robertis R, D'Onofrio M, Ortolani S, Tinazzi Martini P, Cingarlini S,

Keywords: Pancreas, neuroendocrine neoplasms, magnetic resonance imaging, diffusion-weighted imaging,

#1010 Soluble VCAM-1 and Its Relation to Clinical Staging and Histological Grading in Neuroendocrine Neoplasms (NENs)

Introduction: Cellular adhesion molecules play an important role in tumor progression and metastasis.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author:

Authors: Rosiek V, Foltyn W, Strzelczyk J, Zemczak A, Kos-Kudła B,

Keywords: neuroendocrine neoplasms, sVCAM-1, histological grade, clinical stage,

#866 Plasma Chromogranin B as a Marker of Tumor Burden and Radiological Progression in Neuroendocrine Tumors

Introduction: Chromogranin-B (CgB) is expressed in most neuroendocrine tumors (NETs), yet little is understood about its clinical utility as a biomarker.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author:

Authors: Braude D, Bartholomew T, Rossi R, Garcia-Hernandez J, Mullan M,

Keywords: Chromogranin B, midgut NETs, pancreatic NET, progression,